Actual long-term survival after resection of stage III soft tissue sarcoma

Abstract Background Actuarial survival based on the Kaplan–Meier method can overestimate actual long-term survival, especially among those with factors of poor prognosis. Patients American Joint Committee Cancer stage III soft tissue sarcoma (STS) represent a subset high risk STS-specific mortality. Therefore, we aimed to characterize clinicopathological characteristics associated in patients STS. Methods We retrospectively reviewed 116 who underwent surgical resection for STS curative intent between March 2000 and December 2013. Long-term survivors ( n = 61), defined as survived beyond 5 years, were compared short-term 36), died within years. Results Multivariate logistic regression analyses showed that tumor size < 10 cm [odds ratio (OR) 3.95, p 0.047], histological grade 2 (OR 8.12, 0.004), Society Anesthesiologists (ASA) score 1 11.25, 0.001) independently 5-year survival. However, 66% exhibited prognosis: 36% had > 48% 3. Leiomyosarcoma (3 10) was negatively Conclusions Actual after size, grade, ASA score. majority exhibit prognosis, suggesting aggressive treatment should be offered chance these patients.